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Dose schedule modifications for specific goals While the standard schedule targets 12mg maintenance, not every researcher aims for the same outcome
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Specifically, effect estimates (MD [95% CI]) for tirzepatide 15 mg vs semaglutide 2.0 mg, tirzepatide 10 mg vs semaglutide 1.0 mg, and tirzepatide 5 mg vs semaglutide 0.5 mg were, respectively, as follows: 3.87 mmol/mol (8.22 to 0.48)
PMID: 34500605 | doi:10.3390/molecules26175173 Roy K et al
Heart failure: the frequent, forgotten, and often fatal complication of diabetes
This heightened risk is driven by several factors linked to diabetes: Accelerated Atherosclerosis: High blood glucose levels can damage the inner lining of the arteries (the endothelium), making them more susceptible to the buildup of fatty plaques
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